期刊
ORGANIC LETTERS
卷 19, 期 9, 页码 2418-2421出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.7b00968
关键词
-
资金
- National Natural Science Foundation of China [21425415, 21274058]
- National Basic Research Program of China [2015CB856303]
We report herein the development of a Co (III)-catalyzed enaminone-directed C-H amidation method for synthetic access to quinolones, an important heterocyclic scaffold for diverse pharmaceutically active structures. The C-H coupling with,dioxazolones and subsequent deacylation of an installed amide group allow consecutive C-N coupling generation of quinolones with wide-ranging compatible substituent patterns.
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