期刊
ORGANIC LETTERS
卷 19, 期 21, 页码 5884-5887出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.7b02873
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资金
- DST-SERB, India [EMR/2014/000978]
- CSIR
The oxidative cyclization of substituted benzamides with maleimides assisted by 8-aminoquinoline in the presence of a catalytic amount of Co(OAc)(2).4H(2)O provides isoindolone spirosuccinimides in good to excellent yields. The cyclization reaction was compatible with various substituted benzamides and maleimides. A possible reaction mechanism involving the C-H bond activation as a key step was proposed. The competition experiment and deuterium labeling studies were performed to investigate the mechanism of the reaction.
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