期刊
ORGANIC LETTERS
卷 19, 期 20, 页码 5649-5652出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.7b02788
关键词
-
资金
- National Natural Science Foundation of China [21672089, 21472080]
Based upon a radical polar effect, an intermolecular azidoheteroarylation of simple alkenes via a metal-free radical multi component cascade process was achieved. It allows a mild, rapid, and step economic access to a broad range of azidoalkylated heteroaromatics. Given the diversity in transformations of organic azides and medicinally privileged scaffolds of heteroarenes, this strategy enables efficient synthesis and late stage derivatization of drugs and candidates.
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