4.8 Article

Palladium-Catalyzed C(sp2)-H Acetoxylation via Electrochemical Oxidation

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ORGANIC LETTERS
卷 19, 期 11, 页码 2905-2908

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AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.7b01138

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资金

  1. Strategic Priority Research Program of the Chinese Academy of Sciences [XDB20000000]
  2. 1000-Youth Talents Plan, NSF of China [21421-091, 21572245]
  3. S&TCSM of Shanghai [15PJ1410200]

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Palladium-catalyzed arene C(sp2)H acetoxylation has emerged as a powerful tool to construct a carbonoxygen (CO) bond. However, the requirement of stoichiometric chemical oxidants for this transformation possesses a significant disadvantage. To solve this fundamental problem, we now report an anodic oxidation strategy to achieve arene C(sp(2))H acetoxylation.

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