期刊
ORGANIC LETTERS
卷 19, 期 8, 页码 2162-2165出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.7b00797
关键词
-
资金
- National Natural Science Foundation of China [21225208, 21472137, 21532008]
- National Basic Research Program of China (973 Program) [2014CB745100]
- Tianjin Municipal Science & Technology Commission [14JCZDJC33400]
An organocatalytic asymmetric decarboxylative amination reaction of ss-keto acids is described. Under mild reaction conditions, a series of chiral alpha-amino ketones were obtained in good to high yields (up to 99%) and enantioselectivities (up to 95% ee). A chiral 1,2-amino alcohol was synthesized from the corresponding decarboxylative amination product in several steps without loss of enantioselectivity.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据