期刊
ORGANIC LETTERS
卷 19, 期 21, 页码 5786-5789出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.7b02722
关键词
-
资金
- Japan Society for the Promotion of Science (JSPS) [JP17K14483]
- Grants-in-Aid for Scientific Research [17K14483] Funding Source: KAKEN
Preparation of a range of oxazolidinones, including enantioenriched N-aryl-substituted oxazolidinones, in which tetraarylphosphonium salts (TAPS) catalyze the [3 + 2] coupling reaction of isocyanates and epoxides effectively, is described. The key finding is a Bronsted acid/halide ion bifunctional catalyst that can accelerate epoxide ring opening with high regioselectivity. Mechanistic studies disclosed that the ylide generated from TAPS, along with the formation of halohydrins, plays a crucial role in the reaction with isocyanates.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据