Benzothiazole Sulfinate: A Sulfinic Acid Transfer Reagent under Oxidation-Free Conditions

Sulfinic acids are commonly encountered intermediates found in natural product synthesis and medicinal chemistry. However, because of high reactivity, instability; and harsh reaction conditions, they are difficult to synthesize. Herein we have developed an Oxidation-free method to produce sulfinic acids and sulfinate salts,using 2-sulfinyl benzothiazole (BTS). We have, also demonstratd the synthetic usefulness by developing one-pot syntheses of sulfones and sulfonamides.