期刊
ORGANIC LETTERS
卷 19, 期 11, 页码 2897-2900出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.7b01136
关键词
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资金
- National Natural Science Foundation of China [21602062, 21373088, 21425205]
- Ministry of Education [IRT-16R25]
- Shanghai Sailing Program [15YF1403600]
By taking advantage of chirality-transfer strategy, a chemo- and regioselective allylic alkylation of naphthols and phenols with vinylaziridines provides an atom-economic and efficient method for the synthesis of enantioenriched 2-vinyl-2-arylethylamine derivatives. Use of readily available starting materials, a broad substrate scope, high selectivity, mild reaction conditions, as well as versatile functionalizations of the aromatic ethylamine products make this approach very practical and attractive.
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