期刊
ORGANIC LETTERS
卷 19, 期 2, 页码 352-355出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.6b03533
关键词
-
资金
- [JP26221301]
- [JP23105008]
- Grants-in-Aid for Scientific Research [26221301, 26460006, 15J11490, 15H03111] Funding Source: KAKEN
A method for asymmetric alpha-arylation of alpha-amino acid derivatives via memory of chirality has been developed. Addition of axially chiral enolates, generated from alpha-amino acid derivatives, to in situ generated arynes, followed by intramolecular C-acylation of the resulting aryl metallic species, gave benzocyclobutenones with a tetrasubstituted carbon with retention of configuration in up to 99% ee.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据