期刊
ORGANIC LETTERS
卷 19, 期 22, 页码 6156-6159出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.7b03034
关键词
-
资金
- Justus-Liebig University
This letter presents the side-chain iodination of electron-deficient benzylic hydrocarbons at rt using N-hydroxyphthalimide (NHPI) as radical initiator and 1,3-diiodo-5,5-dimethylhydantoin and 3-iodo-1,5,5-trimethylhydantoin (3-ITMH) as iodine source. Addition of a carboxylic acid increased the reactivity due to complex formation with and activation of 3-ITMH by proton transfer and halogen bond formation. No SEAr reaction were observed under the employed reaction conditions. Our method enables convenient product isolation and gives 50-72% yields of isolated products.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据