期刊
ORGANIC & BIOMOLECULAR CHEMISTRY
卷 15, 期 17, 页码 3638-3647出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c7ob00367f
关键词
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资金
- NSFC [21372085]
- National Key Research and Development Program of China [2016YFA0602900]
- Science and Technology Program of Guangzhou [156300075]
- Science and Technology Program of Qingyuan [2014D006]
An Ir(III)-catalyzed relay aryl C-H bond carbenoid insertion cascade of N-aryl-2-pyridinamines with diazo Meldrum's acid has been developed. This method provides an efficient approach to multifunctionalized 1,3-dihydroindol-2-ones with a broad range of functional group tolerance. Furthermore, this protocol could be applied for the concise synthesis of bioactive hematopoietic growth factor analogues.
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