期刊
ORGANIC & BIOMOLECULAR CHEMISTRY
卷 15, 期 5, 页码 1236-1244出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c7ob00026j
关键词
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资金
- National Natural Science Foundation of China (NSFC) [21502037, 21373073, 21672048]
- Natural Science Foundation of Zhejiang Province (ZJNSF) [LY15B020008]
- PCSIRT [IRT 1231]
- Hangzhou Normal University
- Zhejiang Province, China
A rhodium-catalyzed Weinreb amide directed cross-coupling reaction between electron-deficient alkenes is reported, which provides an efficient route for the synthesis of valuable and versatile Weinreb amide functionalized (Z,E)-butadienes. The catalytic system is insensitive to water and oxygen and exhibits broad functional group tolerance. This method also allowed both terminal and internal alkenes as the cross-coupling partners.
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