期刊
ORGANIC & BIOMOLECULAR CHEMISTRY
卷 15, 期 19, 页码 4199-4204出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c7ob00624a
关键词
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An efficient method for regiocontrolled functionalization of 2,3-dihalogenoimidazo[1,2-a] pyridine was developed. This sequence allowed the selective introduction of aryl, heteroaryl, alkyl and alkynyl substituents at both 2- and 3-positions, by using Suzuki-Miyaura and Sonogashira cross-coupling reactions. A library of compounds diversely substituted on 2- and 3-positions can be easily prepared from a common, stable and easily accessible starting material.
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