期刊
ORGANIC & BIOMOLECULAR CHEMISTRY
卷 15, 期 10, 页码 -出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c7ob00122c
关键词
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资金
- University of Delhi
- UGC/CSIR
A copper-catalyzed oxidative coupling reaction of o-phenylenediamines with 2-aryl/heteroarylethylamines using molecular oxygen as an oxidant has been developed. This approach provides a practical and direct access to construct quinoxalines in excellent yields at room temperature. The reaction has a broad substrate scope and exhibits excellent functional-group tolerance. This method could be easily scaled up and applied to the synthesis of biologically active molecules bearing a quinoxaline structural scaffold.
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