期刊
BIOMEDICAL ENGINEERING LETTERS
卷 8, 期 4, 页码 393-398出版社
SPRINGERNATURE
DOI: 10.1007/s13534-018-0084-1
关键词
Amniotic membrane; Wound healing; Menstrual blood-derived stem cells
This is the first study demonstrating the efficacy of menstrual blood-derived stem cell (MenSC) transplantation via decellularized human amniotic membrane (DAM), for the promotion of skin excisional wound repair. The DAM was seeded with MenSCs at the density of 3 x 10(4) cells/cm(2) and implanted onto a rat's 1.50 x 1.50 cm(2) full-thickness excisional wound defect. The results of wound closure and histopathological examinations demonstrated that the MenSC-seeded DAM could significantly improve the wound healing compared with DAM-treatment. All in all, our data indicated that the MenSCs can be a potential source for cell-based therapies to regenerate skin injuries.
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