期刊
CHANNELS
卷 12, 期 1, 页码 356-366出版社
TAYLOR & FRANCIS INC
DOI: 10.1080/19336950.2018.1532255
关键词
ATP-sensitive potassium channel; heart rate; pacemaking; potassium channel; sinoatrial node
资金
- British Heart Foundation [RG/15/15/31742] Funding Source: Medline
Potassium currents determine the resting membrane potential and govern repolarisation in cardiac myocytes. Here, we review the various currents in the sinoatrial node focussing on their molecular and cellular properties and their role in pacemaking and heart rate control. We also describe how our recent finding of a novel ATP-sensitive potassium channel population in these cells fits into this picture.
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