PdCu/Al2O3 catalyst for Sonogashira cross-coupling: effect of a Pd/Cu ratio on the catalytic performance

The catalytic performance of 3 wt% Pd Cu/Al2O3 containing bimetallic alloy Pd-Cu nanoparticles strongly depends on the Pd/Cu ratio in the cross-coupling of phenylacetylene with phenyl iodide, and a maximum activity is attained at Pd/Cu = 1:2.