期刊
OPHTHALMOLOGY
卷 124, 期 10, 页码 1449-1456出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.ophtha.2017.04.021
关键词
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资金
- Carl Zeiss Meditec, Inc
- Heidelberg Engineering
- Topcon Inc.
- Heidelberg Engineering GmbH
- Alcon Laboratories Inc
- Carl Zeiss Meditec Inc
- Pfizer Inc
- Allergan Inc
- Reicherts Inc.
- Optovue Inc
- Topcon Medical Systems
- Quark
- Genentech
- National Eye Institute [U10EY14267, EY08208, EY11008, EY019869, EY13959, EY02115, EY025253]
- Eyesight Foundation of Alabama
- Merck Inc
- Santen Inc
- Research to Prevent Blindness, New York
- New York (Department of Ophthalmology, Columbia University Medical Center)
- New York (Department of Ophthalmology, University of California San Diego)
- Edith C. Blum Foundation, New York, New York
Purpose: To investigate the prevalence of visual field defects in glaucomatous eyes, glaucoma suspects, and ocular hypertensives with 24-2 and 10-2 visual fields. Design: Prospective, cross-sectional study. Participants: Patients with or suspected glaucoma tested with 24-2 and 10-2. Patients were classified into 3 groups on the basis of the presence of glaucomatous optic neuropathy (GON) and 24-2 visual field abnormalities: early glaucoma (GON and abnormal visual field, mean deviation > - 6 decibels [dB]), glaucoma suspects (GON and normal visual field), and ocular hypertensives (normal disc, normal visual field, and intraocular pressure > 22 mmHg). For the classification of visual field abnormalities, 24-2 and 10-2 tests performed on the same visit were analyzed. Main Outcome Measures: Comparison of the prevalence of abnormal 24-2 versus 10-2 visual field results based on cluster criteria in each diagnostic group. Results: A total of 775 eyes (497 patients) were evaluated. A total of 364 eyes had early glaucoma, 303 eyes were glaucoma suspects, and 108 eyes were ocular hypertensives. In the glaucoma group, 16 of the 26 eyes (61.5%) classified as normal based on cluster criteria on 24-2 tests were classified as abnormal on 10-2 visual fields. In eyes with suspected glaucoma, 79 of the 200 eyes (39.5%) classified as normal on the 24-2 test were classified as abnormal on 10-2 visual fields. In ocular hypertensive eyes, 28 of the 79 eyes (35.4%) classified as normal on the 24-2 were classified as abnormal on the 10-2. Patients of African descent were more likely to have an abnormal 10-2 result (67.3 vs. 56.8%, P = 0.009). Conclusions: Central visual field damage seen on the 10-2 test is often missed with the 24-2 strategy in all groups. This finding has implications for the diagnosis of glaucoma and classification of severity. (C) 2017 by the American Academy of Ophthalmology
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