4.1 Article

Reactions of 2H(4H)-chromenes with dinucleophiles: one-step synthesis of 2-(1H-(bi)pyrazol-3-yl)- and 2-(1,4(5)-(benzo)diazepin-4-yl)phenols

期刊

CHEMISTRY OF HETEROCYCLIC COMPOUNDS
卷 54, 期 9, 页码 859-867

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SPRINGER
DOI: 10.1007/s10593-018-2367-y

关键词

chromenes; dipyrazoles; dinucleophiles; rearrangement; Vilsmeier-Haack reagent

资金

  1. Ministry of Education and Science of Ukraine [0115U003159]
  2. New synthetic methods for the design of nitrogen- and sulfur-containing biologically active compounds

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Novel derivatives of 2-(1H-(bi)pyrazol-3-yl)phenols and 2-(1,4(5)-(benzo)diazepin-4-yl)phenols were obtained in the reaction of (4-amino-2H-chromen-2-ylidene)malondialdehyde and 4H-chromen-4-imines with 1,2-, 1,3-, and 1,4-dinucleophiles proceeding as a cascade reaction initiated by the Michael reaction.

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