期刊
EPILEPSY & BEHAVIOR CASE REPORTS
卷 10, 期 -, 页码 65-70出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.ebcr.2018.03.001
关键词
Stimulation; Hypometabolism; Nonketotic; Glucose; Insulin; Circadian
Objectives: To investigate if glucose levels influence seizure patterns. Materials and methods: In a patient with RNS/NeuroPace implanted bi-temporally and type 1 diabetes mellitus, seizure event times and onset locations were matched to continuous tissue glucose. Results: Left focal seizure (IFS, n= 22) glucoses averaged 169 mg/dL, while right focal seizure (RFS, n = 23) glucoses averaged 131 mg/dL (p = 0.03). LFS occurred at mean time 17:02 while RFS occurred at 04:23. LFS spread to the contralateral side (n = 19) more than RFS (n = 2). Conclusion: Seizure onset laterality and spread vary with glucose and time of seizure. (C) 2018 The Authors. Published by Elsevier Inc.
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