期刊
EPILEPSY & BEHAVIOR CASE REPORTS
卷 10, 期 -, 页码 99-101出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.ebcr.2018.07.006
关键词
Verbal memory; Aura; Focal aware seizure; Learning; Hippocampus; Epilepsy
资金
- USA National Science Foundation [NSF RII-2 FEC OIA1632891]
Auras (focal aware seizure: FAS) are subjective ictal events with retained consciousness. Epileptiform activities can disrupt cognitive tasks, but studies are limited to seizures with impaired awareness. As a proof of concept, we examined the cognitive effects of direct electrical stimulation to the left hippocampus which induced a habitual FAS in a patient with left mesial temporal lobe epilepsy. During the induced habitual FAS, verbal memory performance declined significantly as compared to pre-stimulation testing. Tasks measuring auditory working memory and psychomotor processing speed were not affected by the stimulation. The study confirms that FAS can impair episodic verbal memory and learning. (C) 2018 The Authors. Published by Elsevier Inc.
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