期刊
NUTRITION
卷 38, 期 -, 页码 13-19出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.nut.2016.12.020
关键词
Orange juice; Reduced-calorie diet; Body composition; Biochemical biomarkers; Obese; Randomized-controlled trial
资金
- Programa de Apoio ao Desenvolvimento Cientifico da Faculdade de Ciencias Farmaceuticas, UNESP (PADC/FCFAr)
- Citrosuco S.A.
- Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior (CAPES)
Objective: Assumptions have United orange juice (OJ) consumption with weight gain and adverse effects on health due to its sugar content; however, epidemiologic studies have not shown increased risk for overweight or obesity with the consumption of 100% OJ. The aim of this study was to verify whether the combination of a reduced-calorie diet (RCD) and 100% OJ contribute to weight loss, promote changes in glucose and lipid metabolism, and improve diet quality in obese individuals. Methods: A randomized controlled trial with 78 obese patients (age 36 +/- 1 y, body mass index [BMI] 33 +/- 3 kg/m(2)) were enrolled in two groups: Individuals in the OJ group submitted to an RCD that included OJ (500 mL/d), and individuals in the control group submitted to an RCD without OJ. Body composition, biochemical biomarkers, and dietary intake were analyzed over a 12-wk period. Results: Both treatments had similar outcomes regarding body weight (-6.5 kg; P = 0.363), BMI (-2.5 kg/m(2); P = 0.34), lean mass (-1 kg; P = 0.29), fat mass (-5 kg; P = 0.58), body fat (-3%; P = 0.15), and waist-to-hip ratio (-0.1; P = 0.79). Insulin levels in the OJ group decreased by 18% (P = 0.05), homeostasis model assessment-insulin resistance by 33% (P = 0.04), total cholesterol by 24% (P = 0.004), low-density lipoprotein cholesterol by 24% (P <= 0.001), and high-sensitivity C-reactive protein levels by 33% (P = 0.001) compared with the control group. Consumption of energy and nutrients was similar between the two groups, but vitamin C and folate increased by 62% (P <= 0.015) and 39% (P = 0.033), respectively, after OJ intervention. Conclusion: When consumed concomitantly with an RCD, OJ does not inhibit weight loss; ameliorate the insulin sensitivity, lipid profile, or inflammatory status, or contribute nutritionally to the quality of the diet. (C) 2017 The Authors. Published by Elsevier Inc.
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