期刊
NUCLEIC ACIDS RESEARCH
卷 45, 期 W1, 页码 W12-W16出版社
OXFORD UNIV PRESS
DOI: 10.1093/nar/gkx428
关键词
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资金
- National Key Research and Development Program [2016YFC0901603]
- China 863 Program [2015AA020108]
- State Key Laboratory of Protein and Plant Gene Research
- National Program for Support of Top-notch Young Professionals
With advances in next-generation sequencing technologies, numerous novel transcripts in a large number of organisms have been identified. With the goal of fast, accurate assessment of the coding ability of RNA transcripts, we upgraded the coding potential calculator CPC1 to CPC2. CPC2 runs similar to 1000 times faster than CPC1 and exhibits superior accuracy compared with CPC1, especially for long non-coding transcripts. Moreover, the model of CPC2 is species-neutral, making it feasible for ever-growing non-model organism transcriptomes. A mobile-friendly web server, as well as a downloadable standalone package, is freely available at http://cpc2.cbi.pku.edu.cn.
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