期刊
NUCLEIC ACIDS RESEARCH
卷 46, 期 D1, 页码 D343-D347出版社
OXFORD UNIV PRESS
DOI: 10.1093/nar/gkx987
关键词
-
资金
- German Ministry of Education and Research (BMBF) [031L0024A]
- German Research Foundation
- Open Access Fund of the Gottingen University
TFClass is a resource that classifies eukaryotic transcription factors (TFs) according to their DNAbinding domains (DBDs), available online at http://tfclass. bioinf. med. uni-goettingen. de. The classification scheme of TFClass was originally derived for human TFs and is expanded here to the whole taxonomic class of mammalia. Combining information from different resources, checking manually the retrieved mammalian TFs sequences and applying extensive phylogenetic analyses, > 39 000 TFs from up to 41 mammalian species were assigned to the Superclasses, Classes, Families and Subfamilies of TFClass. As a result, TFClass now provides the corresponding sequence collection in FASTA format, sequence logos and phylogenetic trees at different classification levels, predicted TF binding sites for human, mouse, dog and cow genomes as well as links to several external databases. In particular, all those TFs that are also documented in the TRANSFAC (R) database (FACTOR table) have been linked and can be freely accessed. TRANSFAC (R) FACTOR can also be queried through an own search interface.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据