期刊
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS EXTRA
卷 8, 期 1, 页码 128-137出版社
KARGER
DOI: 10.1159/000487851
关键词
Frontotemporal lobar degeneration; Behavioral and psychological symptoms of dementia; Zarit Burden Interview; Family caregivers
资金
- Japan Society for the Promotion of Science (JSPS) [26780306, 26461750]
- Ministry of Health, Labour and Welfare (Research on Dementia) [H27-29 Longevity-General-004]
- Grants-in-Aid for Scientific Research [26780306] Funding Source: KAKEN
Background: Caregiver burden is a serious concern for family caregivers of dementia patients, but its nature is unclear in patients with semantic dementia (SD). This study aimed to clarify caregiver burden for right-(R > L) and left-sided (L > R) predominant SD versus behavioral- variant frontotemporal dementia (bvFTD) patients. Methods: Using the Japanese version of the Zarit Burden Interview (ZBI) and the Neuropsychiatric Inventory, we examined caregiver burden and behavioral and psychological symptoms of dementia (BPSD) in 43 first-visit outpatient/family caregiver dyads (bvFTD, 20 dyads; SD [L > R], 13 dyads; SD [R > L], 10 dyads). Results: We found a significant difference in ZBI score between the 3 diagnostic groups. Post hoc tests revealed a significantly higher ZBI score in the bvFTD than in the SD (L > R) group. The ZBI scores in the SD (L > R) and SD (R > L) groups were not significantly different, although the effect size was large. Caregiver burden was significantly correlated with BPSD scores in all groups and was correlated with activities of daily living and instrumental activities of daily living decline in the bvFTD and SD (R > L) groups. Conclusion: Caregiver burden was highest in the bvFTD group, comparatively high in the SD (R > L) group, and lowest in the SD (L > R) group. Adequate support and intervention for caregivers should be tailored to differences in caregiver burden between these patient groups. (c) 2018 The Author(s) Published by S. Karger AG, Basel
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