4.7 Article

A mitochondria-targeting photothermogenic nanozyme for MRI-guided mild photothermal therapy

期刊

CHEMICAL COMMUNICATIONS
卷 54, 期 100, 页码 14108-14111

出版社

ROYAL SOC CHEMISTRY
DOI: 10.1039/c8cc08570f

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资金

  1. National Science Foundation of China [21525105, 21471164, 21778079, 21771042]
  2. 973 Program [2015CB856301]
  3. Ministry of Education of China [IRT-17R111]
  4. China Postdoctoral Science Foundation [2018M630988]
  5. Fundamental Research Funds for the Central Universities

向作者/读者索取更多资源

Iridium complexes were used as a mitochondria-targeting agent to modify the surface of a photothermogenic nanozyme Fe3O4 nanoparticles (Ir@Fe3O4 NPs). Upon NIR irradiation, Ir@Fe3O4 NPs increase the localized temperature to 42 degrees C which accelerates the catalysis of OH production from H2O2 resulting in excellent mild photothermal therapy.

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