期刊
TROPICAL MEDICINE AND HEALTH
卷 46, 期 -, 页码 -出版社
BMC
DOI: 10.1186/s41182-018-0128-3
关键词
-
资金
- National Institutes of Health [R01AI069145]
- Pasteur Institute of Dakar
BackgroundIn the southeastern Senegal, the report of Plasmodium vivax infections among febrile patients in Kedougou constitutes a new emerging health problem.MethodsSamples from 48 asymptomatic schoolchildren sampled twice a year over 2years were used to explore the reservoir of P. vivax parasite infections in this region. Both Duffy genotyping and Plasmodium species diagnostic assays were performed.ResultsPCR assays detected Plasmodium genomic DNA in 38.5% (74/192) of samples. Pure P. falciparum and P. vivax infections were identified in 79.7% (59/74) and 20.3% (15/74) of samples, respectively. All schoolchildren were classified as Duffy-negative by genotyping. P. vivax infections were detected in five children: in two children during both years, in one child in 2010 and on May 2011, and only in 2010 for the remaining two children.ConclusionsThis unexpectedly high proportion of P. vivax infections in asymptomatic Duffy-negative children highlights to consider vivax malaria as an emerging problem in Senegal.
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