期刊
NEUROSCIENCE RESEARCH
卷 124, 期 -, 页码 8-15出版社
ELSEVIER IRELAND LTD
DOI: 10.1016/j.neures.2017.05.004
关键词
Aging; Cognitive training; Transfer; Brain plasticity; fMRI; Neuropsychological test
资金
- National Research Foundation (NRF) of Korea - Korean Government [NRF-2014S1A3A2044496]
- National Research Foundation of Korea [2014S1A3A2044496] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
The aim of this study was to investigate the changes in cognitive functions and brain activation after multicomponent training of cognitive control in non-demented older adults, utilizing neuropsychological tests and fMRI. We developed and implemented a computerized Multicomponent Training of Cognitive Control (MTCC), characterized by task variability and adaptive procedures, in order to maximize training effects in cognitive control and transfer to other cognitive domains. Twenty-seven community-dwelling adults, aged 64-77 years, without any history of neurological or psychiatric problems, participated in this study (14 in the training group and 13 in the control group). The MTCC was administered to the participants assigned to the training group for 8 weeks, while those in the control group received no training. Neuropsychological tests and fMRI were administered prior to and after the training. Trained participants showed improvements in cognitive control, recognition memory and general cognitive functioning. Furthermore, the MTCC led to an increased brain activation of the regions adjacent to the baseline cognitive control-related areas in the frontoparietal network. Future studies are necessary to confirm our hypothesis that MTCC improves cognitive functioning of healthy elderly individuals by expanding their frontoparietal network that is involved in cognitive control. (C) 2017 The Authors. Published by Elsevier Ireland Ltd.
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