期刊
NEUROSCIENCE LETTERS
卷 652, 期 -, 页码 35-40出版社
ELSEVIER IRELAND LTD
DOI: 10.1016/j.neulet.2016.11.004
关键词
Spinal cord; Regeneration; Sensory neurons; Motor neurons; Grafts
资金
- Christopher and Dana Reeve Foundation
- Medical Research Council
- European Research Council ECMneuro
- Cambridge NHMRC Biomedical Research Centre
- MRC [MR/R004544/1] Funding Source: UKRI
After injury, the adult mammalian central nervous system (CNS) lacks long-distance axon regeneration. This review discusses the similarities and differences of sensory and motor neurons, seeking to understand how to achieve functional sensory and motor regeneration. As these two types of neurons respond differently to axotomy, growth environment and treatment, the future challenge will be on how to achieve full recovery in a way that allows regeneration of both types of fibres simultaneously. (C) 2016 Elsevier Ireland Ltd. All rights reserved.
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