期刊
PHOTONICS
卷 5, 期 4, 页码 -出版社
MDPI
DOI: 10.3390/photonics5040054
关键词
Mueller-matrix; polarization; polarimetry; blood; cancer diagnostics
类别
资金
- Academy of Finland [314369, 311698]
- MEPhI Academic Excellence Project [02, a03.21.0005]
- National Research Tomsk State University Academic D.I. Mendeleev Fund Program
- Academy of Finland (AKA) [314369, 311698, 314369, 311698] Funding Source: Academy of Finland (AKA)
The decomposition of the Mueller matrix of blood films has been carried out using differential matrices with polarized and depolarized parts. The use of a coherent reference wave is applied and the algorithm of digital holographic reconstruction of the field of complex amplitudes is used. On this basis, the 3D Mueller-matrix diffuse tomography methodthe reconstruction of distributions of fluctuations of linear and circular birefringence of depolarizing polycrystalline films of human blood is analytically justified and experimentally tested. The dynamics of the change in the magnitude of the statistical moments of the first-fourth order, which characterize layer-by-layer distributions of fluctuations in the phase anisotropy of the blood film, is examined and analyzed. The most sensitive parameters for prostate cancer are the statistical moments of the third and fourth orders, which characterize the asymmetry and kurtosis of fluctuations in the linear and circular birefringence of blood films. The excellent accuracy of differentiation obtained polycrystalline films of blood from healthy donors and patients with cancer patients was achieved.
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