期刊
NEURON
卷 96, 期 5, 页码 951-953出版社
CELL PRESS
DOI: 10.1016/j.neuron.2017.11.021
关键词
-
资金
- NINDS NIH HHS [R01 NS106668, R01 NS102721] Funding Source: Medline
Re-myelination of CNS nerves after injury is ineffective. Here, Petersen et al. (2017) show that the blood clotting protein fibrinogen inhibits nerve repair by preventing oligodendrocyte progenitor cells from differentiating into myelinating oligodendrocytes. Targeting fibrinogen or its downstream BMP signaling pathway may help with CNS repair.
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