An epidemiological analysis of the level of biosecurity and animal welfare on pig farms in Japan and their effect on the use of veterinary antimicrobials

In Japan the highest use of veterinary antimicrobials is in pig production. To obtain useful information to achieve the best approach to reducing this use, we analyzed the association between the level of on-farm biosecurity and animal welfare with the level of antimicrobial use as recorded on prescriptions on 38 pig farms under contract to veterinarians of the Japanese Association of Swine Veterinarians. To determine the level of welfare we recorded the risk of pre- and post-weaning deaths and the floor space available per fattening pig (m(2)/head). Multivariable linear regression analysis was performed, using biosecurity scores and animal welfare indicators as independent variables and the amount of antimicrobial usage as dependent variables. The results showed that the higher scores for the site condition (location) and external biosecurity scores of the sub-categories 'farm contractors' were strongly associated with the lower use of oral antimicrobials (P<0.05). This suggests that in order to reduce the usage of antimicrobials for herd treatments, farmers should consider the location when building a new farm or pig house and strengthen the entrance requirements for high risk visitors. Regression analysis for the respective antimicrobials showed that the site condition, the biosecurity scores of the sub-categories 'farm contractors', 'pen layouts' (e.g. independence of pens and sites), 'pig flows' (e.g. the completeness of all-in/all-out system) and an animal welfare indicator (i.e. post-weaning mortality risk) were significantly associated with the use of one or more antimicrobials (P<0.05).