期刊
NEUROIMMUNOMODULATION
卷 24, 期 4-5, 页码 183-199出版社
KARGER
DOI: 10.1159/000481824
关键词
Endocannabinoids; Infections; Virus; Bacteria; Parasites
资金
- Programa de Apoyo a Proyectos de Investigacion e Innovacion Tecnologica (PAPIIT) from Direccion General de Asuntos del Personal Academico (DGAPA) [IN-208715]
- Universidad Nacional Autonoma de Mexico (U.N.A.M.)
- Programa de Fondos Sectoriales CB-SEP, Consejo Nacional de Ciencia y Tecnologia (CONACyT) [176803]
- CONACyT
Although the endocannabinoid system (ECS) is involved in the regulation of several physiological processes, including sleep and the immune response, its role during infections has not been fully studied. It is well known that the use of this drug increases susceptibility to infections because of the impact on the modulation of the immune system. Concerning the medicinal or recreational use of marijuana, its influence on the course of an infection, whether this has been caused by bacteria, viruses, parasites, and to a lesser degree, fungi, has been reported. Furthermore, there is evidence suggesting the involvement of the ECS in the control and elimination of infectious agents such as bacteria, viruses, and some protozoa; in the case of fungi, few studies are available so far. The purpose of this review is to present the existing studies related to infections and the ECS, the microbicidal effects of compounds isolated from Cannabis sativa, and the association between marijuana use and the development of rare pathologies in specific diseases. (C) 2017 S. Karger AG, Basel
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