期刊
ORIENTAL JOURNAL OF CHEMISTRY
卷 34, 期 3, 页码 1604-1610出版社
ORIENTAL SCIENTIFIC PUBL CO
DOI: 10.13005/ojc/340354
关键词
Clonazepam; Prussian blue; Ferric chloride; Potassium ferric cyanide; Spectrophotometry
A study aimed to recommend spectrophotometric method for the determination of clonazepam (CLZ.) in pure form and their pharmaceutical tablets by the reaction of sited drug with ferric chloride in presence potassium ferric cyanide in acid medium to form prussian blue complex and determine it by UV-Vis spectrophotometric at 526 nm. The variables that affect the completion of reaction have been carefully optimized. The linearity range was (2-35 mu g.mL(-1)) with a molar absorptivity of 2.8035x10(4) L.mol(-1)cm(-1). The limit of detection was 0.5703 mu g.mL(-1) and Sandell's sensitivity value was 0.0103 mu g.cm(-2). The suggest method was successfully used to estimate clonazepam in commercial formulations.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据