BDNF controls object recognition memory reconsolidation

Reconsolidation restabilizes memory after reactivation. Previously, we reported that the hippocampus is engaged in object recognition memory reconsolidation to allow incorporation of new information into the original engram. Here we show that BDNF is sufficient for this process, and that blockade of BDNF function in dorsal CA(1) impairs updating of the reactivated recognition memory trace. (C) 2017 Elsevier Inc. All rights reserved.