期刊
SYNOPEN
卷 2, 期 1, 页码 25-29出版社
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0037-1609082
关键词
arynes; fused-ring systems; heterocycles; pyrroles; rearrangement; 1,3-dipolar cycloaddition; nitrones
资金
- Italian Ministry of Education, University and Research (MIUR-Rome) [PRIN20109Z2XRJ]
- C.I.N.M.P.I.S.
Reaction of enantiopure 3,4-dialkoxy-pyrroline N-oxides with benzyne affords the expected tetrahydrobenzo[d]pyrrolo[1,2-b]isoxazoles along with an unexpected 2,3-disubstitued-N-phenyl-pyrrole derived from an unprecedented rearrangement of the adduct of nitrone with two molecules of benzyne. A mechanism for the unusual rearrangement is proposed. The benzo[d]isoxazolidine derivatives are conveniently converted into 2-(2-hydroxyphenyl)-3,4-dialkoxypyrrolidines by reductive opening of the N-O bond.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据