4.3 Article

Current Research on the Epidemiology, Pathogenesis, and Management of Necrotizing Enterocolitis

期刊

NEONATOLOGY
卷 111, 期 4, 页码 423-430

出版社

KARGER
DOI: 10.1159/000458462

关键词

Necrotizing enterocolitis; Intestinal microbiota; Premature infants; Inflammation; Toll-like receptor 4; Surgery

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  1. Great Ormond Street Hospital Children's Charity
  2. NIHR Southampton Biomedical Research Centre in Nutrition

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Despite decades of research on necrotizing enterocolitis, we still do not fully understand the pathogenesis of the disease, or how to prevent or how to treat it. However, as a result of recent significant advances in the microbiology, molecular biology, and cell biology of the intestine of preterm infants and infants with necrotizing enterocolitis, there is some hope that research into this devastating disease will yield some important translation into effective prevention, more rapid diagnosis, and novel therapies. (C) 2017 S. Karger AG, Basel

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