期刊
NATURE REVIEWS GENETICS
卷 18, 期 8, 页码 498-512出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nrg.2017.21
关键词
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资金
- European Molecular Biology Organization Long-Term Fellowship [ALT F 841-2014]
- Australian Research Council
- Institucio Catalana de Recerca i Estudis Avancats (ICREA)
- European Research Council [ERC-2007-StG-206883, ERC-2012-Co-616960]
- Ministerio de Economia y Competitividad (MINECO) - European Regional Development Fund (fondos FEDER) [BFU2014-57779-P]
- Secretaria d'Universitats i Recerca del Departament d'Economia i Coneixement de la Generalitat de Catalunya [2014 SCR 619]
The first animals evolved from an unknown single-celled ancestor in the Precambrian period. Recently, the identification and characterization of the genomic and cellular traits of the protists most closely related to animals have shed light on the origin of animals. Comparisons of animals with these unicellular relatives allow us to reconstruct the first evolutionary steps towards animal multicellularity. Here, we review the results of these investigations and discuss their implications for understanding the earliest stages of animal evolution, including the origin of metazoan genes and genome function.
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