期刊
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY
卷 14, 期 3, 页码 141-142出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nrgastro.2017.7
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Drug development in hepatocellular carcinoma had essentially stalled since 2008 when sorafenib was established as the modest standard of care. Now, a positive result in a phase III study evaluating regorafenib challenges us to weigh its clinical significance as well as its real-world benefits and potential harms.
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