相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Robust, universal biomarker assay to detect senescent cells in biological specimens
Konstantinos Evangelou et al.
AGING CELL (2017)
Stromal Senescence By Prolonged CDK4/6 Inhibition Potentiates Tumor Growth
Xiangnan Guan et al.
MOLECULAR CANCER RESEARCH (2017)
Cellular senescence in renal ageing and disease
Ines Sturmlechner et al.
NATURE REVIEWS NEPHROLOGY (2017)
Cellular Senescence Promotes Adverse Effects of Chemotherapy and Cancer Relapse
Marco Demaria et al.
CANCER DISCOVERY (2017)
The senescence-associated secretory phenotype induces cellular plasticity and tissue regeneration
Birgit Ritschka et al.
GENES & DEVELOPMENT (2017)
FOXP1 controls mesenchymal stem cell commitment and senescence during skeletal aging
Hanjun Li et al.
JOURNAL OF CLINICAL INVESTIGATION (2017)
Local clearance of senescent cells attenuates the development of post-traumatic osteoarthritis and creates a pro-regenerative environment
Ok Hee Jeon et al.
NATURE MEDICINE (2017)
Osteoarthritis Year in Review 2016: biomarkers (biochemical markers)
A. Mobasheri et al.
OSTEOARTHRITIS AND CARTILAGE (2017)
Senescent cells expose and secrete an oxidized form of membrane-bound vimentin as revealed by a natural polyreactive antibody
David Frescas et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Cellular senescence mediates fibrotic pulmonary disease
Marissa J. Schafer et al.
NATURE COMMUNICATIONS (2017)
Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging
Marjolein P. Baar et al.
CELL (2017)
Injury-Induced Senescence Enables In Vivo Reprogramming in Skeletal Muscle
Aurelie Chiche et al.
CELL STEM CELL (2017)
Longitudinal assessment of carotid atherosclerosis after Radiation Therapy using Computed Tomography: A case control Study
Michele Anzidei et al.
EUROPEAN RADIOLOGY (2016)
Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice
Jianhui Chang et al.
NATURE MEDICINE (2016)
Chronic senolytic treatment alleviates established vasomotor dysfunction in aged or atherosclerotic mice
Carolyn M. Roos et al.
AGING CELL (2016)
Metformin-mediated increase in DICER1 regulates microRNA expression and cellular senescence
Nicole Noren Hooten et al.
AGING CELL (2016)
Identification of a novel senolytic agent, navitoclax, targeting the Bcl-2 family of anti-apoptotic factors
Yi Zhu et al.
AGING CELL (2016)
Discovery of piperlongumine as a potential novel lead for the development of senolytic agents
Yingying Wang et al.
AGING-US (2016)
Diabetes Medications as Monotherapy or Metformin-Based Combination Therapy for Type 2 Diabetes A Systematic Review and Meta-analysis
Nisa M. Maruthur et al.
ANNALS OF INTERNAL MEDICINE (2016)
Distinct Functions of Senescence-Associated Immune Responses in Liver Tumor Surveillance and Tumor Progression
Tobias Eggert et al.
CANCER CELL (2016)
A BH3 Mimetic for Killing Cancer Cells
Douglas R. Green
CELL (2016)
MLL1 is essential for the senescence-associated secretory phenotype
Brian C. Capell et al.
GENES & DEVELOPMENT (2016)
HMGB2 orchestrates the chromatin landscape of senescence-associated secretory phenotype gene loci
Katherine M. Aird et al.
JOURNAL OF CELL BIOLOGY (2016)
NOTCH1 mediates a switch between two distinct secretomes during senescence
Matthew Hoare et al.
NATURE CELL BIOLOGY (2016)
p16Ink4a-induced senescence of pancreatic beta cells enhances insulin secretion
Aharon Helman et al.
NATURE MEDICINE (2016)
Cellular senescence and aging
C-K Yeh
ORAL DISEASES (2016)
Osteoarthritis year in review 2015: soluble biomarkers and the BIPED criteria
A. C. Bay-Jensen et al.
OSTEOARTHRITIS AND CARTILAGE (2016)
Senescent intimal foam cells are deleterious at all stages of atherosclerosis
Bennett G. Childs et al.
SCIENCE (2016)
Tissue damage and senescence provide critical signals for cellular reprogramming in vivo
Lluc Mosteiro et al.
SCIENCE (2016)
Physiological and Pharmacological Control of BAK, BAX, and Beyond
Mark P. A. Luna-Vargas et al.
TRENDS IN CELL BIOLOGY (2016)
Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis
Megan K. Ruhland et al.
NATURE COMMUNICATIONS (2016)
Directed elimination of senescent cells by inhibition of BCL-W and BCL-XL
Reut Yosef et al.
NATURE COMMUNICATIONS (2016)
BRD4 Connects Enhancer Remodeling to Senescence Immune Surveillance
Nilgun Tasdemir et al.
CANCER DISCOVERY (2016)
Stromal-Initiated Changes in the Bone Promote Metastatic Niche Development
Xianmin Luo et al.
CELL REPORTS (2016)
Antibody Drug Conjugates for Cancer Therapy
Paul Polakis
PHARMACOLOGICAL REVIEWS (2016)
Cellular senescence: from growth arrest to immunogenic conversion
D. G. A. Burton et al.
AGE (2015)
The Achilles' heel of senescent cells: from transcriptome to senolytic drugs
Yi Zhu et al.
AGING CELL (2015)
Cellular senescence-like features of lung fibroblasts derived from idiopathic pulmonary fibrosis patients
Hagai Yanai et al.
AGING-US (2015)
The unfolded protein response and cellular senescence. A Review in the Theme: Cellular Mechanisms of Endoplasmic Reticulum Stress Signaling in Health and Disease
Olivier Pluquet et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2015)
SHP2: a new target for pro-senescence cancer therapies
Manuel Serrano
EMBO JOURNAL (2015)
Shp2 signaling suppresses senescence in PyMT-induced mammary gland cancer in mice (vol 34, pg 1493, 2015)
Linxiang Lan et al.
EMBO JOURNAL (2015)
Proteolytic Processing of Interleukin-1 Family Cytokines: Variations on a Common Theme
Inna S. Afonina et al.
IMMUNITY (2015)
Recent insights into the cellular biology of atherosclerosis
Ira Tabas et al.
JOURNAL OF CELL BIOLOGY (2015)
Cell Autonomous and Non-Autonomous Effects of Senescent Cells in the Skin
Marco Demaria et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2015)
MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation
Remi-Martin Laberge et al.
NATURE CELL BIOLOGY (2015)
Cellular senescence in aging and age-related disease: from mechanisms to therapy
Bennett G. Childs et al.
NATURE MEDICINE (2015)
OARSI Clinical Trials Recommendations: Soluble biomarker assessments in clinical trials in osteoarthritis
V. B. Kraus et al.
OSTEOARTHRITIS AND CARTILAGE (2015)
Biomarkers of early stage osteoarthritis, rheumatoid arthritis and musculoskeletal health
Usman Ahmed et al.
SCIENTIFIC REPORTS (2015)
Development of PD-1/PD-L1 Pathway in Tumor Immune Microenvironment and Treatment for Non-Small Cell Lung Cancer
Jiabei He et al.
SCIENTIFIC REPORTS (2015)
Forging a signature of in vivo senescence
Norman E. Sharpless et al.
NATURE REVIEWS CANCER (2015)
Aging increases CCN1 expression leading to muscle senescence
Jie Du et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2014)
Targeting Apoptosis Pathways for New Cancer Therapeutics
Longchuan Bai et al.
ANNUAL REVIEW OF MEDICINE, VOL 65 (2014)
Mechanism-based pharmacokinetic/pharmacodynamic meta-analysis of navitoclax (ABT-263) induced thrombocytopenia
Aksana Kaefer et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2014)
An Essential Role for Senescent Cells in Optimal Wound Healing through Secretion of PDGF-AA
Marco Demaria et al.
DEVELOPMENTAL CELL (2014)
Senescence and apoptosis: dueling or complementary cell fates?
Bennett G. Childs et al.
EMBO REPORTS (2014)
Assessment of sarcopenia and changes in body composition after neoadjuvant chemotherapy and associations with clinical outcomes in oesophageal cancer
Connie Yip et al.
EUROPEAN RADIOLOGY (2014)
Senescence-associated release of transmembrane proteins involves proteolytic processing by ADAM17 and microvesicle shedding
Timo Effenberger et al.
FASEB JOURNAL (2014)
Incidence and risk factors of significant carotid artery stenosis in asymptomatic survivors of head and neck cancer after radiotherapy
Jennifer A. Dorth et al.
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK (2014)
The Mdm Network and Its Regulation of p53 Activities: A Rheostat of Cancer Risk
Christine M. Eischen et al.
HUMAN MUTATION (2014)
Aging and Risk of Severe, Disabling, Life-Threatening, and Fatal Events in the Childhood Cancer Survivor Study
Gregory T. Armstrong et al.
JOURNAL OF CLINICAL ONCOLOGY (2014)
International Society of Geriatric Oncology Consensus on Geriatric Assessment in Older Patients With Cancer
Hans Wildiers et al.
JOURNAL OF CLINICAL ONCOLOGY (2014)
Role of arterial telomere dysfunction in hypertension: relative contributions of telomere shortening and telomere uncapping
R. Garrett Morgan et al.
JOURNAL OF HYPERTENSION (2014)
Aberrant expression of decoy receptor 3 in human breast cancer: relevance to lymphangiogenesis
Qiuwan Wu et al.
JOURNAL OF SURGICAL RESEARCH (2014)
Necessary and Sufficient Role for a Mitosis Skip in Senescence Induction
Yoshikazu Johmura et al.
MOLECULAR CELL (2014)
Siltuximab for multicentric Castleman's disease: a randomised, double-blind, placebo-controlled trial
Frits van Rhee et al.
LANCET ONCOLOGY (2014)
Geriatric muscle stem cells switch reversible quiescence into senescence
Pedro Sousa-Victor et al.
NATURE (2014)
The role of senescent cells in ageing
Jan M. van Deursen
NATURE (2014)
Gut microbiota-generated metabolites in animal health and disease
Won-Jae Lee et al.
NATURE CHEMICAL BIOLOGY (2014)
Rejuvenation of the muscle stem cell population restores strength to injured aged muscles
Benjamin D. Cosgrove et al.
NATURE MEDICINE (2014)
p38 MAPK signaling underlies a cell-autonomous loss of stem cell self-renewal in skeletal muscle of aged mice
Jennifer D. Bernet et al.
NATURE MEDICINE (2014)
Cellular senescence: from physiology to pathology
Daniel Munoz-Espin et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2014)
PAI-1-regulated extracellular proteolysis governs senescence and survival in Klotho mice
Mesut Eren et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Characterization of novel markers of senescence and their prognostic potential in cancer
M. Althubiti et al.
CELL DEATH & DISEASE (2014)
Metformin inhibits the senescence-associated secretory phenotype by interfering with IKK/NF-B activation
Olga Moiseeva et al.
AGING CELL (2013)
Increased expression of senescence markers in cystic fibrosis airways
Bernard M. Fischer et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2013)
Causes of Genome Instability
Andres Aguilera et al.
ANNUAL REVIEW OF GENETICS, VOL 47 (2013)
Aging, Cellular Senescence, and Cancer
Judith Campisi
ANNUAL REVIEW OF PHYSIOLOGY, VOL 75 (2013)
Constitutive HER2 Signaling Promotes Breast Cancer Metastasis through Cellular Senescence
Pier Davide Angelini et al.
CANCER RESEARCH (2013)
Programmed Cell Senescence during Mammalian Embryonic Development
Daniel Munoz-Espin et al.
CELL (2013)
Senescence Is a Developmental Mechanism that Contributes to Embryonic Growth and Patterning
Mekayla Storer et al.
CELL (2013)
DNA-Damaging Agents in Cancer Chemotherapy: Serendipity and Chemical Biology
Kahlin Cheung-Ong et al.
CHEMISTRY & BIOLOGY (2013)
Senescence-associated secretory phenotype in a mouse model of bleomycin-induced lung injury
Kazutetsu Aoshiba et al.
EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY (2013)
Cell fusion induced by ERVWE1 or measles virus causes cellular senescence
Anna Chuprin et al.
GENES & DEVELOPMENT (2013)
HMGA2 expression in white adipose tissue linking cellular senescence with diabetes
Dominique Nadine Markowski et al.
GENES AND NUTRITION (2013)
Redox Control of the Senescence Regulator Interleukin-1α and the Secretory Phenotype
Donald A. McCarthy et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Accelerated Aging, Decreased White Matter Integrity, and Associated Neuropsychological Dysfunction 25 Years After Pediatric Lymphoid Malignancies
Ilse Schuitema et al.
JOURNAL OF CLINICAL ONCOLOGY (2013)
p53-dependent chemokine production by senescent tumor cells supports NKG2D-dependent tumor elimination by natural killer cells
Alexandre Iannello et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2013)
Combinatorial antigen recognition with balanced signaling promotes selective tumor eradication by engineered T cells
Christopher C. Kloss et al.
NATURE BIOTECHNOLOGY (2013)
A complex secretory program orchestrated by the inflammasome controls paracrine senescence
Juan Carlos Acosta et al.
NATURE CELL BIOLOGY (2013)
The ATM protein kinase: regulating the cellular response to genotoxic stress, and more
Yosef Shiloh et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2013)
Granule exocytosis mediates immune surveillance of senescent cells
A. Sagiv et al.
ONCOGENE (2013)
Osteoarthritis as an inflammatory disease (osteoarthritis is not osteoarthrosis!)
F. Berenbaum
OSTEOARTHRITIS AND CARTILAGE (2013)
Senescent Cardiac Fibroblast Is Critical for Cardiac Fibrosis after Myocardial Infarction
Fuli Zhu et al.
PLOS ONE (2013)
Mitochondrial DNA damage induces apoptosis in senescent cells
R-M Laberge et al.
CELL DEATH & DISEASE (2013)
p53 DNA Binding Cooperativity Is Essential for Apoptosis and Tumor Suppression In Vivo
Oleg Timofeev et al.
CELL REPORTS (2013)
p21 Both Attenuates and Drives Senescence and Aging in BubR1 Progeroid Mice
Darren J. Baker et al.
CELL REPORTS (2013)
Caveolin-1 Deficiency Protects from Pulmonary Fibrosis by Modulating Epithelial Cell Senescence in Mice
Pooja Shivshankar et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2012)
Targeted Cargo Delivery in Senescent Cells Using Capped Mesoporous Silica Nanoparticles
Alessandro Agostini et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2012)
Tumor Suppression in the Absence of p53-Mediated Cell-Cycle Arrest, Apoptosis, and Senescence
Tongyuan Li et al.
CELL (2012)
Phase II Study of Single-Agent Navitoclax (ABT-263) and Biomarker Correlates in Patients with Relapsed Small Cell Lung Cancer
Charles M. Rudin et al.
CLINICAL CANCER RESEARCH (2012)
Senescence determines the fate of activated rat pancreatic stellate cells
Brit Fitzner et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2012)
Cellular Senescence Limits Regenerative Capacity and Allograft Survival
Heidi Braun et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2012)
Lamin B1 loss is a senescence-associated biomarker
Adam Freund et al.
MOLECULAR BIOLOGY OF THE CELL (2012)
Astrocyte Senescence as a Component of Alzheimer's Disease
Rekha Bhat et al.
PLOS ONE (2012)
Macrophages, Nitric Oxide and microRNAs Are Associated with DNA Damage Response Pathway and Senescence in Inflammatory Bowel Disease
Jane J. Sohn et al.
PLOS ONE (2012)
Plasminogen activator inhibitor 1 - insulin-like growth factor binding protein 3 cascade regulates stress-induced senescence
David J. Elzi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Down-regulation of DcR2 sensitizes androgen-dependent prostate cancer LNCaP cells to TRAIL-induced apoptosis
David Vindrieux et al.
CANCER CELL INTERNATIONAL (2011)
p38MAPK is a novel DNA damage response-independent regulator of the senescence-associated secretory phenotype
Adam Freund et al.
EMBO JOURNAL (2011)
Control of the senescence-associated secretory phenotype by NF-κB promotes senescence and enhances chemosensitivity
Yuchen Chien et al.
GENES & DEVELOPMENT (2011)
DNMT3a plays a role in switches between doxorubicin-induced senescence and apoptosis of colorectal cancer cells
Yu Zhang et al.
INTERNATIONAL JOURNAL OF CANCER (2011)
Tumor Suppressor and Aging Biomarker p16INK4a Induces Cellular Senescence without the Associated Inflammatory Secretory Phenotype
Jean-Philippe Coppe et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
DNA-SCARS: distinct nuclear structures that sustain damage-induced senescence growth arrest and inflammatory cytokine secretion
Francis Rodier et al.
JOURNAL OF CELL SCIENCE (2011)
Identification of a Panel of Novel Serum Osteoarthritis Biomarkers
Patricia Fernandez-Puente et al.
JOURNAL OF PROTEOME RESEARCH (2011)
Senescence surveillance of pre-malignant hepatocytes limits liver cancer development
Tae-Won Kang et al.
NATURE (2011)
Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
Darren J. Baker et al.
NATURE (2011)
Atherosclerosis: current pathogenesis and therapeutic options
Christian Weber et al.
NATURE MEDICINE (2011)
Activation of nuclear factor-kappa B signalling promotes cellular senescence
E. Rovillain et al.
ONCOGENE (2011)
Canakinumab (ACZ885, a fully human IgG1 anti-IL-1 beta mAb) induces sustained remission in pediatric patients with cryopyrin-associated periodic syndrome (CAPS)
Jasmin B. Kuemmerle-Deschner et al.
ARTHRITIS RESEARCH & THERAPY (2011)
Aberrant expression and function of death receptor-3 and death decoy receptor-3 in human cancer (Review)
Zhicheng Ge et al.
EXPERIMENTAL AND THERAPEUTIC MEDICINE (2011)
Cell-free nucleic acids as biomarkers in cancer patients
Heidi Schwarzenbach et al.
NATURE REVIEWS CANCER (2011)
Ionizing radiation-induced long-term expression of senescence markers in mice is independent of p53 and immune status
Oanh N. L. Le et al.
AGING CELL (2010)
Concept of Vulnerable/Unstable Plaque
Aloke V. Finn et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2010)
Developing a minimum standard of care for treating people with osteoarthritis of the hip and knee
Lyn March et al.
BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY (2010)
Persistent Telomere Damage Induces Bypass of Mitosis and Tetraploidy
Teresa Davoli et al.
CELL (2010)
Absence of p53-dependent apoptosis leads to UV radiation hypersensitivity, enhanced immunosuppression and cellular senescence
Omid Tavana et al.
CELL CYCLE (2010)
Anti-ageing and rejuvenating effects of quercetin
Niki Chondrogianni et al.
EXPERIMENTAL GERONTOLOGY (2010)
PD-1 signalling in CD4+T cells restrains their clonal expansion to an immunogenic stimulus, but is not critically required for peptide-induced tolerance
Joanne E. Konkel et al.
IMMUNOLOGY (2010)
A novel type of cellular senescence that can be enhanced in mouse models and human tumor xenografts to suppress prostate tumorigenesis
Andrea Alimonti et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
Targeted deletion of the 9p21 non-coding coronary artery disease risk interval in mice
Axel Visel et al.
NATURE (2010)
The matricellular protein CCN1 induces fibroblast senescence and restricts fibrosis in cutaneous wound healing
Joon-Il Jun et al.
NATURE CELL BIOLOGY (2010)
A Human-Like Senescence-Associated Secretory Phenotype Is Conserved in Mouse Cells Dependent on Physiological Oxygen
Jean-Philippe Coppe et al.
PLOS ONE (2010)
Serial Coronary CT Angiography-Verified Changes in Plaque Characteristics as an End Point Evaluation of Effect of Statin Intervention
Kaori Inoue et al.
JACC-CARDIOVASCULAR IMAGING (2010)
SENESCENCE Senescence in tumours: evidence from mice and humans
Manuel Collado et al.
NATURE REVIEWS CANCER (2010)
p38MAPK Controls Expression of Multiple Cell Cycle Inhibitors and Islet Proliferation with Advancing Age
Esther Sook Miin Wong et al.
DEVELOPMENTAL CELL (2009)
BMP4 Mediates Oxidative Stress-induced Retinal Pigment Epithelial Cell Senescence and Is Overexpressed in Age-related Macular Degeneration
DanHong Zhu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
CCL5 Secreted by Senescent Aged Fibroblasts Induces Proliferation of Prostate Epithelial Cells and Expression of Genes that Modulate Angiogenesis
D. Eyman et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2009)
Intracellular versus extracellular granzyme B in immunity and disease: challenging the dogma
Wendy Anne Boivin et al.
LABORATORY INVESTIGATION (2009)
Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion
Francis Rodier et al.
NATURE CELL BIOLOGY (2009)
A crucial role for adipose tissue p53 in the regulation of insulin resistance
Tohru Minamino et al.
NATURE MEDICINE (2009)
Cell surface-bound IL-1α is an upstream regulator of the senescence-associated IL-6/IL-8 cytokine network
Arturo V. Orjalo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Enhanced susceptibility of cyclin kinase inhibitor p21 knockout mice to high fat diet induced atherosclerosis
Ashwani K. Khanna
JOURNAL OF BIOMEDICAL SCIENCE (2009)
Senescence-messaging secretome: SMS-ing cellular stress
Thomas Kuilman et al.
NATURE REVIEWS CANCER (2009)
IL-6 receptor inhibition with tocilizumab improves treatment outcomes in patients with rheumatoid arthritis refractory to anti-tumour necrosis factor biologicals: results from a 24-week multicentre randomised placebo-controlled trial
P. Emery et al.
ANNALS OF THE RHEUMATIC DISEASES (2008)
Efficacy and safety of rilonacept (Interleukin-1 Trap) in patients with cryopyrin-associated periodic syndromes
Hal M. Hoffman et al.
ARTHRITIS AND RHEUMATISM (2008)
ABT-263: A potent and orally bioavailable Bcl-2 family inhibitor
Christin Tse et al.
CANCER RESEARCH (2008)
Senescence-associated exosome release from human prostate cancer cells
Brian D. Lehmann et al.
CANCER RESEARCH (2008)
Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network
Thomas Kuilman et al.
CELL (2008)
Chemokine signaling via the CXCR2 receptor reinforces senescence
Juan C. Acosta et al.
CELL (2008)
Senescence of activated stellate cells limits liver fibrosis
Valery Krizhanovsky et al.
CELL (2008)
Health effects of quercetin: From antioxidant to nutraceutical
Agnes W. Boots et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2008)
Opposing roles for p16Ink4a and p19Arf in senescence and ageing caused by BubR1 insufficiency
Darren J. Baker et al.
NATURE CELL BIOLOGY (2008)
Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor
Jean-Philippe Coppe et al.
PLOS BIOLOGY (2008)
Estimates of the prevalence of arthritis and other rheumatic conditions in the United States
Reva C. Lawrence et al.
ARTHRITIS AND RHEUMATISM (2008)
Second generation inhibitors of BCR-ABL for the treatment of imatinib-resistant chronic myeloid leukaemia
Ellen Weisberg et al.
NATURE REVIEWS CANCER (2007)
Coronary artery aneurysm induced by Kawasaki disease in children show features typical senescence
Ryuji Fukazawa et al.
CIRCULATION JOURNAL (2007)
Senescent human fibroblasts increase the early growth of xenograft tumors via matrix metalloproteinase secretion
Dan Liu et al.
CANCER RESEARCH (2007)
Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas
Wen Xue et al.
NATURE (2007)
Decoy receptor-2 small interfering RNA (siRNA) strategy employing three different siRNA constructs in combination defeats adenovirus-transferred tumor necrosis factor-related apoptosis-inducing ligand resistance in lung cancer cells
Cigdem Aydin et al.
HUMAN GENE THERAPY (2007)
Cellular senescence: when bad things happen to good cells
Judith Campisi et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
Accelerated cellular senescence in degenerate intervertebral discs: a possible role in the pathogenesis of intervertebral disc degeneration
Christine Lyn Le Maitre et al.
ARTHRITIS RESEARCH & THERAPY (2007)
Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints
Jirina Bartkova et al.
NATURE (2006)
Mitogenic signalling and the p16INK4a-Rb pathway cooperate to enforce irreversible cellular senescence
Akiko Takahashi et al.
NATURE CELL BIOLOGY (2006)
The chemokine growth-regulated oncogene 1 (Gro-1) links RAS signaling to the senescence of stromal fibroblasts and ovarian tumorigenesis
Gong Yang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Chronic health conditions in adult survivors of childhood cancer
Kevin C. Oeffinger et al.
NEW ENGLAND JOURNAL OF MEDICINE (2006)
Expression of p14ARF, p15INK4b, p16INK4a, and DCR2 increases during prostate cancer progression
Zhihong Zhang et al.
MODERN PATHOLOGY (2006)
Requirement for pre-existing of p21 to prevent doxorubicin-induced apoptosis through inhibition of caspase-3 activation
J. J. Tang et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2006)
Target of rapamycin inhibitors (Sirolimus and Everolimus) for primary immunosuppression of kidney transplant recipients: A systematic review and meta-analysis of randomized trials
Angela C. Webster et al.
TRANSPLANTATION (2006)
Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis
ZB Chen et al.
NATURE (2005)
Cellular senescence in the glaucomatous outflow pathway
PB Liton et al.
EXPERIMENTAL GERONTOLOGY (2005)
Osteoarthritis - An untreatable disease?
HA Wieland et al.
NATURE REVIEWS DRUG DISCOVERY (2005)
Endogenous p53 protects vascular smooth muscle cells from apoptosis and reduces atherosclerosis in ApoE knockout mice
J Mercer et al.
CIRCULATION RESEARCH (2005)
Therapeutic effect of the combination of etanercept and methotrexate compared with each treatment alone in patients with rheumatoid arthritis: double-blind randomised controlled trial
L Klareskog et al.
LANCET (2004)
The differential impact of p16INK4a or p19ARF deficiency on cell growth and tumorigenesis
NE Sharpless et al.
ONCOGENE (2004)
Ink4a/Arf expression is a biomarker of aging
J Krishnamurthty et al.
JOURNAL OF CLINICAL INVESTIGATION (2004)
Constitutional aneuploidy and cancer predisposition caused by biallelic mutations in BUB1B
S Hanks et al.
NATURE GENETICS (2004)
Chondrocyte senescence, joint loading and osteoarthritis
JA Martin et al.
CLINICAL ORTHOPAEDICS AND RELATED RESEARCH (2004)
Real-time imaging of transcriptional activation in live cells reveals rapid up-regulation of the cyclin-dependent kinase inhibitor gene CDKN1A in replicative cellular senescence
U Herbig et al.
AGING CELL (2003)
Bleomycin induces cellular senescence in alveolar epithelial cells
K Aoshiba et al.
EUROPEAN RESPIRATORY JOURNAL (2003)
Reversal of human cellular senescence:: roles of the p53 and p16 pathways
CM Beauséjour et al.
EMBO JOURNAL (2003)
Senescence-enhanced oxidative stress is associated with deficiency of mitochondrial cytochrome c oxidase in vascular endothelial cells
MG Xin et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2003)
Endothelial cell senescence in human atherosclerosis - Role of telomere in endothelial dysfunction
T Minamino et al.
CIRCULATION (2002)
Treatment of rheumatoid arthritis with anakinra, a recombinant human interleukin-1 receptor antagonist, in combination with methotrexate - Results of a twenty-four-week, multicenter, randomized, double-blind, placebo-controlled trial
S Cohen et al.
ARTHRITIS AND RHEUMATISM (2002)
Senescent fibroblasts promote epithelial cell growth and tumorigenesis: A link between cancer and aging
A Krtolica et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Loss of p16Ink4a confers susceptibility to metastatic melanoma in mice
P Krimpenfort et al.
NATURE (2001)
Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis
NE Sharpless et al.
NATURE (2001)
The growth suppressor p27Kip1 protects against diet-induced atherosclerosis
A Díez-Juan et al.
FASEB JOURNAL (2001)
Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence
N Ohtani et al.
NATURE (2001)
Posttranslational modifications of p53 in replicative senescence overlapping but distinct from those induced by DNA damage
K Webley et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)
分享论文
