期刊
NATURE NEUROSCIENCE
卷 20, 期 12, 页码 1680-+出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/s41593-017-0009-9
关键词
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资金
- National Institutes of Health (NIH) [R01MH101214]
- Human Frontier Science Program [RGP0015/2016]
- NARSAD [23169, 21227]
- National Natural Science Foundation of China [81428010, 91432106]
- China Postdoctoral Science Foundation [2016M590316]
- Louis Feil Trust
- Stanley Family Foundation
- Simons Foundation [344904]
- Wodecroft Foundation
Experience-driven synaptic plasticity in the lateral amygdala is thought to underlie the formation of associations between sensory stimuli and an ensuing threat. However, how the central amygdala participates in such a learning process remains unclear. Here we show that PKC-delta-expressing central amygdala neurons are essential for the synaptic plasticity underlying learning in the lateral amygdala, as they convey information about the unconditioned stimulus to lateral amygdala neurons during fear conditioning.
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