相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Mitochondrial protein-linked DNA breaks perturb mitochondrial gene transcription and trigger free radical-induced DNA damage
Shih-Chieh Chiang et al.
SCIENCE ADVANCES (2017)
Pure cerebellar ataxia linked to large C9orf72 repeat expansion
Philippe Corcia et al.
AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION (2016)
Autophagy Regulates Chromatin Ubiquitination in DNA Damage Response through Elimination of SQSTM1/p62
Yanan Wang et al.
MOLECULAR CELL (2016)
Prevalent, Dynamic, and Conserved R-Loop Structures Associate with Specific Epigenomic Signatures in Mammals
Lionel A. Sanz et al.
MOLECULAR CELL (2016)
C9ORF72 poly(GA) aggregates sequester and impair HR23 and nucleocytoplasmic transport proteins
Yong-Jie Zhang et al.
NATURE NEUROSCIENCE (2016)
Regulation of DNA double-strand break repair by ubiquitin and ubiquitin-like modifiers
Petra Schwertman et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2016)
Bidirectional coupling of splicing and ATM signaling in response to transcription-blocking DNA damage
Maria Tresini et al.
RNA BIOLOGY (2016)
The core spliceosome as target and effector of non-canonical ATM signalling
Maria Tresini et al.
NATURE (2015)
A second-generation Irish genome-wide association study for amyotrophic lateral sclerosis
Russell L. McLaughlin et al.
NEUROBIOLOGY OF AGING (2015)
Topoisomerase-mediated chromosomal break repair: an emerging player in many games
Mohamed E. Ashour et al.
NATURE REVIEWS CANCER (2015)
Alzheimer disease and amyotrophic lateral sclerosis: an etiopathogenic connection
Xiaochuan Wang et al.
ACTA NEUROPATHOLOGICA (2014)
Sequestration of multiple RNA recognition motif-containing proteins by C9orf72 repeat expansions
Johnathan Cooper-Knock et al.
BRAIN (2014)
Partial inhibition of Cdk1 in G2 phase overrides the SAC and decouples mitotic events
Rachael A. McCloy et al.
CELL CYCLE (2014)
C9orf72 nucleotide repeat structures initiate molecular cascades of disease
Aaron R. Haeusler et al.
NATURE (2014)
BRCA2 prevents R-loop accumulation and associates with TREX-2 mRNA export factor PCID2
Vaibhav Bhatia et al.
NATURE (2014)
TDP2 protects transcription from abortive topoisomerase activity and is required for normal neural function
Fernando Gomez-Herreros et al.
NATURE GENETICS (2014)
Aberrant topoisomerase-1 DNA lesions are pathogenic in neurodegenerative genome instability syndromes
Sachin Katyal et al.
NATURE NEUROSCIENCE (2014)
ATM Deficiency Results in Accumulation of DNA-Topoisomerase I Covalent Intermediates in Neural Cells
Meryem Alagoz et al.
PLoS One (2014)
Out of Balance: R-loops in Human Disease
Matthias Groh et al.
PLOS GENETICS (2014)
Genome-Wide Profiling of Yeast DNA: RNA Hybrid Prone Sites with DRIP-Chip
Yujia A. Chan et al.
PLOS GENETICS (2014)
Brain distribution of dipeptide repeat proteins in frontotemporal lobar degeneration and motor neurone disease associated with expansions in C9ORF72
Yvonne S. Davidson et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2014)
Reduced C9orf72 gene expression in c9FTD/ALS is caused by histone trimethylation, an epigenetic event detectable in blood
Veronique V. Belzil et al.
ACTA NEUROPATHOLOGICA (2013)
Corticobasal and ataxia syndromes widen the spectrum of C9ORF72 hexanucleotide expansion disease
S. G. Lindquist et al.
CLINICAL GENETICS (2013)
Senataxin, Defective in the Neurodegenerative Disorder Ataxia with Oculomotor Apraxia 2, Lies at the Interface of Transcription and the DNA Damage Response
Oezlem Yuece et al.
MOLECULAR AND CELLULAR BIOLOGY (2013)
R Loops Are Linked to Histone H3 S10 Phosphorylation and Chromatin Condensation
Maikel Castellano-Pozo et al.
MOLECULAR CELL (2013)
53BP1 is a reader of the DNA-damage-induced H2A Lys 15 ubiquitin mark
Amelie Fradet-Turcotte et al.
NATURE (2013)
The ATM protein kinase: regulating the cellular response to genotoxic stress, and more
Yosef Shiloh et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2013)
RAN proteins and RNA foci from antisense transcripts in C9ORF72 ALS and frontotemporal dementia
Tao Zu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
RNF168 ubiquitylates 53BP1 and controls its response to DNA double-strand breaks
Miyuki Bohgaki et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Dipeptide repeat proteins are present in the p62 positive inclusions in patients with frontotemporal lobar degeneration and motor neurone disease associated with expansions in C9ORF72
David M. A. Mann et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2013)
ATM and the Molecular Pathogenesis of Ataxia Telangiectasia
Peter J. McKinnon
ANNUAL REVIEW OF PATHOLOGY: MECHANISMS OF DISEASE, VOL 7 (2012)
ATM mediates interdependent activation of p53 and ERK through formation of a ternary complex with p-p53 and p-ERK in response to DNA damage
Jee-In Heo et al.
MOLECULAR BIOLOGY REPORTS (2012)
R Loops: From Transcription Byproducts to Threats to Genome Stability
Andres Aguilera et al.
MOLECULAR CELL (2012)
Nuclear accumulation of HDAC4 in ATM deficiency promotes neurodegeneration in ataxia telangiectasia
Jiali Li et al.
NATURE MEDICINE (2012)
Length of normal alleles of C9ORF72 GGGGCC repeat do not influence disease phenotype
Nicola J. Rutherford et al.
NEUROBIOLOGY OF AGING (2012)
To live or to die: a matter of processing damaged DNA termini in neurons
Sherif F. El-Khamisy
EMBO MOLECULAR MEDICINE (2011)
Replication stress induces 53BP1-containing OPT domains in G1 cells
Jeanine A. Harrigan et al.
JOURNAL OF CELL BIOLOGY (2011)
Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS
Mariely DeJesus-Hernandez et al.
NEURON (2011)
Optimised and Rapid Pre-clinical Screening in the SOD1G93A Transgenic Mouse Model of Amyotrophic Lateral Sclerosis (ALS)
Richard J. Mead et al.
PLOS ONE (2011)
ATM-Dependent Chromatin Changes Silence Transcription In cis to DNA Double-Strand Breaks
Niraj M. Shanbhag et al.
CELL (2010)
53BP1 promotes ATM activity through direct interactions with the MRN complex
Ji-Hoon Lee et al.
EMBO JOURNAL (2010)
53BP1-dependent robust localized KAP-1 phosphorylation is essential for heterochromatic DNA double-strand break repair
Angela T. Noon et al.
NATURE CELL BIOLOGY (2010)
RNF168 Binds and Amplifies Ubiquitin Conjugates on Damaged Chromosomes to Allow Accumulation of Repair Proteins
Carsten Doil et al.
CELL (2009)
The RIDDLE Syndrome Protein Mediates a Ubiquitin-Dependent Signaling Cascade at Sites of DNA Damage
Grant S. Stewart et al.
CELL (2009)
ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin
Aaron A. Goodarzi et al.
MOLECULAR CELL (2008)
An Infinitely Expandable Cloning Strategy plus Repeat-Proof PCR for Working with Multiple shRNA
Glen John Mcintyre et al.
PLOS ONE (2008)
Mechanism of R-loop formation at immunoglobulin class switch sequences
Deepankar Roy et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
Attenuated DNA damage repair by trichostatin a through BRCA1 suppression
Yin Zhang et al.
RADIATION RESEARCH (2007)
Role of Nbs1 in the activation of the Atm kinase revealed in humanized mouse models
S Difilippantonio et al.
NATURE CELL BIOLOGY (2005)
An essential function for NBS1 in the prevention of ataxia and cerebellar defects
PO Frappart et al.
NATURE MEDICINE (2005)
Defective DNA single-strand break repair in spinocerebellar ataxia with axonal neuropathy-1
SF El-Khamisy et al.
NATURE (2005)
DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation
CJ Bakkenist et al.
NATURE (2003)
分享论文
