期刊
NATURE METHODS
卷 14, 期 9, 页码 865-+出版社
NATURE PORTFOLIO
DOI: 10.1038/NMETH.4380
关键词
-
资金
- Deutsche Forschungsgemeinschaft
- NIH [DP2-HG-009623]
- National Human Genome Research Institute [UM1HG008901]
High-throughput single-cell RNA sequencing has transformed our understanding of complex cell populations, but it does not provide phenotypic information such as cell-surface protein levels. Here, we describe cellular indexing of transcriptomes and epitopes by sequencing (CITE-seq), a method in which oligonucleotide-labeled antibodies are used to integrate cellular protein and transcriptome measurements into an efficient, single-cell readout. CIT-seq is compatible with existing single-cell sequencing approaches and scales readily with throughput increases.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据