4.8 Article

A quantitative and multiplexed approach to uncover the fitness Landscape of tumor suppression in vivo

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

Molecular definition of a metastatic lung cancer state reveals a targetable CD109-Janus kinase-Stat axis

Chen-Hua Chuang et al.

NATURE MEDICINE (2017)

Article Biochemistry & Molecular Biology

Dual Chromatin and Cytoskeletal Remodeling by SETD2

In Young Park et al.

Article Biochemistry & Molecular Biology

Development of a Comprehensive Genotype-to-Fitness Map of Adaptation-Driving Mutations in Yeast

Sandeep Venkataram et al.

Article Biochemical Research Methods

An in vivo multiplexed small-molecule screening platform

Barbara M. Gruner et al.

NATURE METHODS (2016)

Article Biochemical Research Methods

DADA2: High-resolution sample inference from Illumina amplicon data

Benjamin J. Callahan et al.

NATURE METHODS (2016)

Article Biochemistry & Molecular Biology

Tumor suppressor properties of the splicing regulatory factor RBM10

Jordi Hernandez et al.

RNA BIOLOGY (2016)

Article Multidisciplinary Sciences

The histone H3.3K36M mutation reprograms the epigenome of chondroblastomas

Dong Fang et al.

SCIENCE (2016)

Article Biochemical Research Methods

Error filtering, pair assembly and error correction for next-generation sequencing reads

Robert C. Edgar et al.

BIOINFORMATICS (2015)

Article Multidisciplinary Sciences

Barcoding reveals complex clonal dynamics of de novo transformed human mammary cells

Long V. Nguyen et al.

NATURE (2015)

Article Multidisciplinary Sciences

Quantitative evolutionary dynamics using high-resolution lineage tracking

Sasha F. Levy et al.

NATURE (2015)

Article Biochemistry & Molecular Biology

Studying clonal dynamics in response to cancer therapy using high-complexity barcoding

Hyo-eun C. Bhang et al.

NATURE MEDICINE (2015)

Article Multidisciplinary Sciences

Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer

Naiyer A. Rizvi et al.

SCIENCE (2015)

Review Biochemistry & Molecular Biology

The extracellular matrix modulates the hallmarks of cancer

Michael W. Pickup et al.

EMBO REPORTS (2014)

Article Cell Biology

The evolution of thymic lymphomas in p53 knockout mice

Crissy Dudgeon et al.

GENES & DEVELOPMENT (2014)

Review Biochemistry & Molecular Biology

Recent Progress on Liver Kinase B1 (LKB1): Expression, Regulation, Downstream Signaling and Cancer Suppressive Function

Ren-You Gan et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2014)

Article Oncology

Nullifying the CDKN2AB Locus Promotes Mutant K-ras Lung Tumorigenesis

Katja Schuster et al.

MOLECULAR CANCER RESEARCH (2014)

Article Multidisciplinary Sciences

Comprehensive molecular profiling of lung adenocarcinoma

Eric A. Collisson et al.

NATURE (2014)

Article Multidisciplinary Sciences

Rapid modelling of cooperating genetic events in cancer through somatic genome editing

Francisco J. Sanchez-Rivera et al.

NATURE (2014)

Article Multidisciplinary Sciences

Clonal dynamics of native haematopoiesis

Jianlong Sun et al.

NATURE (2014)

Article Multidisciplinary Sciences

CRISPR-mediated direct mutation of cancer genes in the mouse liver

Wen Xue et al.

NATURE (2014)

Article Multidisciplinary Sciences

Discovery and saturation analysis of cancer genes across 21 tumour types

Michael S. Lawrence et al.

NATURE (2014)

Article Biochemistry & Molecular Biology

Easy quantitative assessment of genome editing by sequence trace decomposition

Eva K. Brinkman et al.

NUCLEIC ACIDS RESEARCH (2014)

Article Multidisciplinary Sciences

Genetic Screens in Human Cells Using the CRISPR-Cas9 System

Tim Wang et al.

SCIENCE (2014)

Article Oncology

Obligate Progression Precedes Lung Adenocarcinoma Dissemination

Deborah R. Caswell et al.

CANCER DISCOVERY (2014)

Article Multidisciplinary Sciences

Diverse and heritable lineage imprinting of early haematopoietic progenitors

Shalin H. Naik et al.

NATURE (2013)

Article Multidisciplinary Sciences

Mutational heterogeneity in cancer and the search for new cancer-associated genes

Michael S. Lawrence et al.

NATURE (2013)

Article Multidisciplinary Sciences

Mutational landscape and significance across 12 major cancer types

Cyriac Kandoth et al.

NATURE (2013)

Article Biochemistry & Molecular Biology

Mapping the Hallmarks of Lung Adenocarcinoma with Massively Parallel Sequencing

Marcin Imielinski et al.

Review Cell Biology

Making sense of cancer genomic data

Lynda Chin et al.

GENES & DEVELOPMENT (2011)

Review Oncology

Hypoxia and Senescence: The Impact of Oxygenation on Tumor Suppression

Scott M. Welford et al.

MOLECULAR CANCER RESEARCH (2011)

Article Multidisciplinary Sciences

Lkb1 regulates cell cycle and energy metabolism in haematopoietic stem cells

Daisuke Nakada et al.

NATURE (2010)

Article Multidisciplinary Sciences

Stage-specific sensitivity to p53 restoration during lung cancer progression

David M. Feldser et al.

NATURE (2010)

Review Cell Biology

Tumor suppressors and cell metabolism: a recipe for cancer growth

Russell G. Jones et al.

GENES & DEVELOPMENT (2009)

Article Biochemical Research Methods

Conditional mouse lung cancer models using adenoviral or lentiviral delivery of Cre recombinase

Michel DuPage et al.

NATURE PROTOCOLS (2009)

Article Multidisciplinary Sciences

Somatic mutations affect key pathways in lung adenocarcinoma

Li Ding et al.

NATURE (2008)

Article Biochemistry & Molecular Biology

Dynamic histone H3 methylation during gene induction: HYPB/Setd2 mediates all H3K36 trimethylation

John W. Edmunds et al.

EMBO JOURNAL (2008)

Article Multidisciplinary Sciences

LKB1 modulates lung cancer differentiation and metastasis

Hongbin Ji et al.

NATURE (2007)

Article Biochemistry & Molecular Biology

A spatially and temporally restricted mouse model of soft tissue sarcoma

David G. Kirsch et al.

NATURE MEDICINE (2007)

Review Physics, Multidisciplinary

Power laws, Pareto distributions and Zipf's law

MEJ Newman

CONTEMPORARY PHYSICS (2005)

Review Oncology

Modelling the molecular circuitry of cancer

WC Hahn et al.

NATURE REVIEWS CANCER (2002)

Review Biochemistry & Molecular Biology

Cancer Modeling in the modern era: Progress and challenges

T Van Dyke et al.