相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Fine-mapping inflammatory bowel disease loci to single-variant resolution
Hailiang Huang et al.
NATURE (2017)
Discovery of stimulation-responsive immune enhancers with CRISPR activation
Dimitre R. Simeonov et al.
NATURE (2017)
Genome-wide characterization of mammalian promoters with distal enhancer functions
Lan T. M. Dao et al.
NATURE GENETICS (2017)
Lineage-Specific Genome Architecture Links Enhancers and Non-coding Disease Variants to Target Gene Promoters
Biola M. Javierre et al.
CELL (2016)
A Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response
Britt Adamson et al.
CELL (2016)
Local regulation of gene expression by lncRNA promoters, transcription and splicing
Jesse M. Engreitz et al.
NATURE (2016)
Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9
John G. Doench et al.
NATURE BIOTECHNOLOGY (2016)
HiChIP: efficient and sensitive analysis of protein-directed genome architecture
Maxwell R. Mumbach et al.
NATURE METHODS (2016)
Cardiometabolic risk loci share downstream cis- and trans-gene regulation across tissues and diseases
Oscar Franzen et al.
SCIENCE (2016)
High-resolution interrogation of functional elements in the noncoding genome
Neville E. Sanjana et al.
SCIENCE (2016)
Systematic mapping of functional enhancer-promoter connections with CRISPR interference
Charles P. Fulco et al.
SCIENCE (2016)
Integrative functional genomics identifies regulatory mechanisms at coronary artery disease loci
Clint L. Miller et al.
NATURE COMMUNICATIONS (2016)
Genetic Control of Chromatin States in Humans Involves Local and Distal Chromosomal Interactions
Fabian Grubert et al.
CELL (2015)
Chromatin architecture reorganization during stem cell differentiation
Jesse R. Dixon et al.
NATURE (2015)
Integrative analysis of haplotype-resolved epigenomes across human tissues
Danny Leung et al.
NATURE (2015)
Conserved epigenomic signals in mice and humans reveal immune basis of Alzheimer's disease
Elizabeta Gjoneska et al.
NATURE (2015)
Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers
Suna Onengut-Gumuscu et al.
NATURE GENETICS (2015)
Mapping long-range promoter contacts in human cells with high-resolution capture Hi-C
Borbala Mifsud et al.
NATURE GENETICS (2015)
FTO Obesity Variant Circuitry and Adipocyte Browning in Humans
Melina Claussnitzer et al.
NEW ENGLAND JOURNAL OF MEDICINE (2015)
Chromatin extrusion explains key features of loop and domain formation in wild-type and engineered genomes
Adrian L. Sanborn et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Coronary Artery Disease Associated Transcription Factor TCF21 Regulates Smooth Muscle Precursor Cells That Contribute to the Fibrous Cap
Sylvia T. Nurnberg et al.
PLOS GENETICS (2015)
Genetic and epigenetic variation in the lineage specification of regulatory T cells
Aaron Arvey et al.
ELIFE (2015)
De novo transcriptome profiling of highly purified human lymphocytes primary cells
Raoul J. P. Bonnal et al.
SCIENTIFIC DATA (2015)
Genetic and epigenetic fine mapping of causal autoimmune disease variants
Kyle Kai-How Farh et al.
NATURE (2015)
HiC-Pro: an optimized and flexible pipeline for Hi-C data processing
Nicolas Servant et al.
GENOME BIOLOGY (2015)
Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation
Luke A. Gilbert et al.
CELL (2014)
A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin Looping
Suhas S. P. Rao et al.
CELL (2014)
A comparative encyclopedia of DNA elements in the mouse genome
Feng Yue et al.
NATURE (2014)
The alarmin IL-33 promotes regulatory T-cell function in the intestine
Chris Schiering et al.
NATURE (2014)
Obesity-associated variants within FTO form long-range functional connections with IRX3
Scott Smemo et al.
NATURE (2014)
The NHGRI GWAS Catalog, a curated resource of SNP-trait associations
Danielle Welter et al.
NUCLEIC ACIDS RESEARCH (2014)
Interindividual variation in human T regulatory cells
Alessandra Ferraro et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Intersection of population variation and autoimmunity genetics in human T cell activation
Chun Jimmie Ye et al.
SCIENCE (2014)
Polarization of the Effects of Autoimmune and Neurodegenerative Risk Alleles in Leukocytes
Towfique Raj et al.
SCIENCE (2014)
In search of the determinants of enhancer-promoter interaction specificity
Joris van Arensbergen et al.
TRENDS IN CELL BIOLOGY (2014)
Beyond GWASs: Illuminating the Dark Road from Association to Function
Stacey L. Edwards et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2013)
DNA targeting specificity of RNA-guided Cas9 nucleases
Patrick D. Hsu et al.
NATURE BIOTECHNOLOGY (2013)
Large-scale association analysis identifies new risk loci for coronary artery disease
Panos Deloukas et al.
NATURE GENETICS (2013)
Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position
Jason D. Buenrostro et al.
NATURE METHODS (2013)
Human Disease-Associated Genetic Variation Impacts Large Intergenic Non-Coding RNA Expression
Vinod Kumar et al.
PLOS GENETICS (2013)
Foxp3 Exploits a Pre-Existent Enhancer Landscape for Regulatory T Cell Lineage Specification
Robert M. Samstein et al.
CELL (2012)
Extensive Promoter-Centered Chromatin Interactions Provide a Topological Basis for Transcription Regulation
Guoliang Li et al.
CELL (2012)
Topological domains in mammalian genomes identified by analysis of chromatin interactions
Jesse R. Dixon et al.
NATURE (2012)
ChromHMM: automating chromatin-state discovery and characterization
Jason Ernst et al.
NATURE METHODS (2012)
Human Blood CXCR5+CD4+ T Cells Are Counterparts of T Follicular Cells and Contain Specific Subsets that Differentially Support Antibody Secretion
Rimpei Morita et al.
IMMUNITY (2011)
A unique chromatin signature uncovers early developmental enhancers in humans
Alvaro Rada-Iglesias et al.
NATURE (2011)
Genomic views of STAT function in CD4+ T helper cell differentiation
John J. O'Shea et al.
NATURE REVIEWS IMMUNOLOGY (2011)
Genome-wide association study in alopecia areata implicates both innate and adaptive immunity
Lynn Petukhova et al.
NATURE (2010)
Mediator and cohesin connect gene expression and chromatin architecture
Michael H. Kagey et al.
NATURE (2010)
Histone H3K27ac separates active from poised enhancers and predicts developmental state
Menno P. Creyghton et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Genetic Variants Associated with Lp(a) Lipoprotein Level and Coronary Disease
Robert Clarke et al.
NEW ENGLAND JOURNAL OF MEDICINE (2009)
Comprehensive Mapping of Long-Range Interactions Reveals Folding Principles of the Human Genome
Erez Lieberman-Aiden et al.
SCIENCE (2009)
Genetic Mapping in Human Disease
David Altshuler et al.
SCIENCE (2008)
A common variant on chromosome 9p21 affects the risk of myocardial infarction
Anna Helgadottir et al.
SCIENCE (2007)
A common allele on chromosome 9 associated with coronary heart disease
Ruth McPherson et al.
SCIENCE (2007)
Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cells
Eva V. Acosta-Rodriguez et al.
NATURE IMMUNOLOGY (2007)
Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome
Nathaniel D. Heintzman et al.
NATURE GENETICS (2007)
Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
E Bettelli et al.
NATURE (2006)