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Human embryonic kidney (HEK293) cells express endogenous voltage-gated sodium currents and Nav1.7 sodium channels
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Four Ca2+ Ions Activate TRPM2 Channels by Binding in Deep Crevices near the Pore but Intracellularly of the Gate
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Intracellular calcium activates TRPM2 and its alternative spliced isoforms
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2'-deoxy cyclic adenosine 5'-diphosphate ribose derivatives: Importance of the 2'-hydroxyl motif for the antagonistic activity of 8-substituted cADPR derivatives
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Chemotaxis of mouse bone marrow neutrophils and dendritic cells is controlled by ADP-Ribose, the major product generated by the CD38 enzyme reaction
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K-T Yang et al.
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Metabolite of SIR2 reaction modulates TRPM2 ion channel
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Nicotinic acid adenine dinucleotide phosphate and cyclic ADP-ribose regulate TRPM2 channels in T lymphocytes
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TRPM2 is elevated in the tMCAO stroke model, transcriptionally regulated, and functionally expressed in C13 microglia
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Activation of T cell calcium influx by the second messenger ADP-ribose
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TRPM2 channel opening in response to oxidative stress is dependent on activation of poly(ADP-ribose) polymerase
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BRITISH JOURNAL OF PHARMACOLOGY (2004)
Expression profile of the transient receptor potential (TRP) family in neutrophil granulocytes:: evidence for currents through long TRP channel 2 induced by ADP-ribose and NAD
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Activation of the cation channel long transient receptor potential channel 2 (LTRPC2) by hydrogen peroxide -: A splice variant reveals a mode of activation independent of ADP-ribose
E Wehage et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
High-performance liquid chromatographic technique for detection of a fluorescent analogue of ADP-ribose in isolated blood vessel preparations
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Detection of poly(ADP-ribose) polymerase activation in oxidatively stressed cells and tissues using biotinylated NAD substrate
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LTRPC2 Ca2+-permeable channel activated by changes in redox status confers susceptibility to cell death
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Immunocyte Ca2+ influx system mediated by LTRPC2
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SCIENCE (2001)
ADP-ribose gating of the calcium-permeable LTRPC2 channel revealed by Nudix motif homology
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Molecular cloning, chromosomal localization, tissue mRNA levels, bacterial expression, and enzymatic properties of human NMN adenylyltransferase
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