4.8 Article

Minimum information about a single amplified genome (MISAG) and a metagenome-assembled genome (MIMAG) of bacteria and archaea

期刊

NATURE BIOTECHNOLOGY
卷 35, 期 8, 页码 725-731

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NATURE PUBLISHING GROUP
DOI: 10.1038/nbt.3893

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资金

  1. Laboratory Directed Research and Development Program of Lawrence Berkeley National Laboratory under US National Science Foundation [DEB-1441717, OCE-1232982, OCE-1136488, OCE-1335810]
  2. European Research Council (ERC) [310039]
  3. Swedish Foundation for Strategic Research [SSF-FFL5]
  4. Australian Laureate Fellowship from the Australian Research Council [FL150100038]
  5. Gordon and Betty Moore Foundation [GBMF3801]
  6. NSF [DEB-1441717, OCE-1335810]
  7. United States National Science Foundation (NSF) Microbial Long Term Ecological Research program [NTL-LTER DEB-1440297]
  8. INSPIRE award [DEB-1344254]
  9. National Institute of Food and Agriculture, US Department of Agriculture [1002996]
  10. National Institutes of Health, National Institute of Dental and Craniofacial Research [5R01DE024463]
  11. [DE-AC02-05CH11231]
  12. Russian Science Foundation [14-50-00069] Funding Source: Russian Science Foundation
  13. Division Of Environmental Biology
  14. Direct For Biological Sciences [1441717] Funding Source: National Science Foundation
  15. Division Of Ocean Sciences
  16. Directorate For Geosciences [1335810] Funding Source: National Science Foundation
  17. Office Of The Director
  18. Office Of Internatl Science &Engineering [0968421] Funding Source: National Science Foundation
  19. Office Of The Director
  20. Office Of Internatl Science &Engineering [GRANTS:13792270] Funding Source: National Science Foundation
  21. BBSRC [BB/I02612X/1] Funding Source: UKRI
  22. European Research Council (ERC) [310039] Funding Source: European Research Council (ERC)
  23. Biotechnology and Biological Sciences Research Council [BB/I02612X/1] Funding Source: researchfish

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We present two standards developed by the Genomic Standards Consortium (GSC) for reporting bacterial and archaeal genome sequences. Both are extensions of the Minimum Information about Any (x) Sequence (MIxS). The standards are the Minimum Information about a Single Amplified Genome (MISAG) and the Minimum Information about a Metagenome-Assembled Genome (MIMAG), including, but not limited to, assembly quality, and estimates of genome completeness and contamination. These standards can be used in combination with other GSC checklists, including the Minimum Information about a Genome Sequence (MIGS), Minimum Information about a Metagenomic Sequence (MIMS), and Minimum Information about a Marker Gene Sequence (MIMARKS). Community-wide adoption of MISAG and MIMAG will facilitate more robust comparative genomic analyses of bacterial and archaeal diversity.

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