期刊
NATURAL PRODUCT RESEARCH
卷 32, 期 19, 页码 2366-2369出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2017.1410815
关键词
Penicillium griseofulvum; bicyclic lactam; polyketide; antibacterial activity
A pair of enantiomeric 4-oxabicyclic[4.3.0]lactam derivatives, (+)- and (-)-penicilactam A (1), and one new polyketide derivative penicitrinone F (2) were isolated from the marine-derived fungus Penicillium griseofulvum GT-10. Their structures and absolute configurations were elucidated through extensive spectroscopic analyses combined with the calculated ECD spectra. Penicitrinone F (2) had moderate inhibitory activity towards Bacillus subtilis with a MIC value of 6.3M. [GRAPHICS] .
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