期刊
NATURAL PRODUCT RESEARCH
卷 31, 期 22, 页码 2690-2694出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2017.1290620
关键词
Cholinesterase inhibitors; Iranian traditional medicine; A. catechu; S. aromaticum; C. chinensis; P. vulgare; I. turpethum
资金
- Research Council of Tehran University of Medical Sciences [94-02-96-29579]
In this study, in vitro evaluation of cholinesterase inhibitory (ChEI) activity of various plants including betel nuts (Areca catechu L.), clove buds (Syzygium aromaticum L.), aerial parts of dodder (Cuscuta chinensis Lam.), common polypody rhizomes (Polypodium vulgare L.) and turpeth roots (Ipomoea turpethum R.Br.) which were recommended for the treatment of AD symptoms in Iranian Traditional Medicine (ITM) is reported. Among them, aqueous extract of A. catechu L. was found as the most potent anti-AChE (IC50 = 32.00 mu g/mL) and anti-BChE (IC50 = 48.81 +/- 0.1200 mu g/mL) agent. Aqueous extract of betel nuts as AChE inhibitor (IC50 = 32.00 mu g/mL). [GRAPHICS] .
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