期刊
NATURAL PRODUCT RESEARCH
卷 33, 期 4, 页码 464-471出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2017.1396593
关键词
Laurencia majuscula; halogenated tricyclic sesquiterpene; omphalane; rhodolaurane; antibacterial activity
资金
- Sabah Biodiversity Centre [GL00070]
Three new halogenated tricyclic sesquiterpenes, omphalaurediol (1), rhodolaurenones B (2) and C (3) were isolated together with nine known haloganated sesquiterpenes such as rhodolaurenone A (4), rhodolaureol (5), isorhodolaureol (6), (-)-laurencenone D (7), elatol (8), (+)-deschloroelatol (9), cartilagineol (10), (+)-laurencenone B (11) and 2-chloro-3-hydroxy-alpha-chamigren-9-one (12) from a population of Bornean red algae Laurencia majuscula. The structures of three new metabolites were determined based on their spectroscopic data (IR, 1D and 2D NMR, and MS). These compounds showed antibacterial activity against three human pathogenic bacteria (Escherichia coli, Salmonella typhi and Vibrio cholera). [GRAPHICS] .
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